KW2449

Datasheet MSDS
Catalog Number
SBCR10092
Product Name
KW2449
CAS Number
1000669-72-6
Molecular Formula
C20H20N4O
Molecular Weight
332.4
Purity
98.43%
Solubility
DMSO: 62 mg/mL (186.5 mM) Ethanol: 62 mg/mL (186.5 mM) Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Kw-2449 is a multi-target inhibitor that is most effective against Flt3 with an IC50 of 6.6nM, moderately effective against BCR chemicalbook-ABL and AuroraA. There was no inhibitory effect on PDGFRβ, IGF-1R and EGFR. Phase1.
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