CEP28122

Datasheet MSDS
Catalog Number
SALK10058
Product Name
CEP28122
CAS Number
1022958-60-6
Synonyms
CEP 28122, CEP-28122
Molecular Formula
C28H35ClN6O3
Molecular Weight
539.07
Purity
100.00%
Solubility
DMSO: 10 mM ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
CEP-28122 is a highly potent and selective orally active ALK inhibitor with a favorable pharmaceutical and pharmacokinetic profile and robust and selective pharmacologic efficacy against ALK-positive human cancer cells and tumor xenograft models in mice. Anaplastic lymphoma kinase (ALK) is constitutively activated in a number of human cancer types due to chromosomal translocations, point mutations, and gene amplification and has emerged as an excellent molecular target for cancer therapy.
Target
ALK
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