Uprosertib

Datasheet MSDS
Catalog Number
SAKT13469
Product Name
Uprosertib
CAS Number
1047634-65-0
Synonyms
GSK2141795 , GSK795 , GSK795 , GSK2141795
Molecular Formula
C18H16Cl2F2N4O2
Molecular Weight
429.25
Purity
99.54%
Solubility
DMSO: 79 mg/mL (184 mM) Ethanol: 76 mg/mL (177.1 mM) Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Uprosertib (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively. Phase 2.
Target
Akt1, Akt2, Akt3
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