Catalog Number
SALK10024
Product Name
GSK1838705A
CAS Number
1116235-97-2
Molecular Formula
C27H29FN8O3
Molecular Weight
532.57
Purity
100.00%
Solubility
DMSO: 53.3 mg/mL (100 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
GSK1838705A is an effective IGF-1R inhibitor with an IC50 of 2.0 nM, moderately effective on IR and ALK with an IC50 of 1.6 nM and 0.5 nM, respectively. It has almost no activity against other protein kinases.
Target
ALK, IGF-1R, Insulin Receptor, JNK3, RSK1
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