AP26113

Datasheet MSDS
Catalog Number
SALK10022
Product Name
AP26113
CAS Number
1197958-12-5
Synonyms
ALK-IN-1, AP26113-analog, Brigatinib
Molecular Formula
C26H34ClN6O2P
Molecular Weight
529.01
Purity
100.00%
Solubility
DMSO: 42 mg/mL (79.4 mM) Ethanol: 98 mg/mL (185.3 mM) Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
AP26113 is a potent ALK inhibitor with an IC50 of 0.62 nM, which overcomes Crizotinib resistance mediated by L1196M mutation
Target
ALK, EGFR (C797S/del19), EGFR (del19), IGF-1R
Inquiry

new products