Catalog Number
SCAS20781
Product Name
CKI-7
CAS Number
120615-25-0
Molecular Formula
C11H12ClN3O2S
Molecular Weight
285.75
Solubility
DMSO: 25 mg/mL (87.49 mM), Need ultrasonic ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.
Target
CK1
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