WZ4002

Datasheet MSDS
Catalog Number
SEGF10222
Product Name
WZ4002
CAS Number
1213269-23-8
Molecular Formula
C25H27ClN6O3
Molecular Weight
494.18
Purity
98.12%
Solubility
DMSO: 11 mg/mL (22.3 mM) Ethanol: <1 mg/mL Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
WZ4002 is a novel, mutation-selective EGFR inhibitor with IC50 of 2 nM/8 nM when acting on EGFR(L858R)/(T790M); There is no inhibitory effect on ERBB2 phosphorylation (T798I).
Target
EGFR (L858R), EGFR (L858R/T790M)
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