Catalog Number
SBMI11870
Product Name
PTC-209 HBr
CAS Number
1217022-63-3
Synonyms
PTC-209 hydrobromide , PTC-209 hydrobromide
Molecular Formula
C17H13Br2N5OS·HBr
Molecular Weight
576.1
Purity
98.0%
Solubility
DMSO: 93 mg/mL (161.4 mM) Ethanol: <1 mg/mL Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
PTC-209 HBr is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs).
Target
BMI-1
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