Catalog Number
SANT22511
Product Name
Delpazolid
CAS Number
1219707-39-7
Synonyms
LCB01-0371
Molecular Formula
C14H17FN4O3
Molecular Weight
308.31
Purity
99.87%
Solubility
DMSO: 30 mg/mL (97.30 mM), Need ultrasonic and warming ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Delpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacteriostatic activity against Staphylococcus aureus.
Target
Others
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