Torin 2

Datasheet MSDS
Catalog Number
SATM14115
Product Name
Torin 2
CAS Number
1223001-51-1
Molecular Formula
C24H15F3N4O
Molecular Weight
432.4
Purity
99.47%
Solubility
DMSO: 8.7 mg/mL (20 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Torin 2(IC50=0.25 nM), a specific and effective mTOR inhibitor, is the 800-fold greater specific activity for mTOR than PI3K and improves pharmacokinetic properties. The EC50 of Torin 2 for ATM/ATR/DNA-PK inhibition is 28 nM/35 nM/118 nM, respectively.
Target
ATM, ATR, DNA-PK, mTOR
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