A1155463

Datasheet MSDS
Catalog Number
SBCL10869
Product Name
A1155463
CAS Number
1235034-55-5
Synonyms
A-1155463 , A 1155463
Molecular Formula
C35H32FN5O4S2
Molecular Weight
669.79
Purity
99.00%
Solubility
Ethanol: 100 mg/mL (149.3 mM) DMSO: 100 mg/mL (149.3 mM) Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2 and related proteins BCL-W(Ki=19 nM) and MCL-1(Ki>440 nM).
Target
Bcl-2, Bcl-w, Bcl-xL, Mcl-1
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