ABT199

Datasheet MSDS
Catalog Number
SBCL10834
Product Name
ABT199
CAS Number
1257044-40-8
Synonyms
ABT 199 , ABT-199 , GDC-0199 , Venetoclax
Molecular Formula
C45H50ClN7O7S
Molecular Weight
868.44
Purity
99.92%
Solubility
DMSO: 93 mg/mL (107.1 mM) Ethanol: <1 mg/mL Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
ABT-199 is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders of magnitude less avidly to Bcl-xL, and Bcl-W (Kis = 48 and 245 nM, respectively).
Target
Bcl-2, Bcl-w, Bcl-xL, Mcl-1
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