Pyrazolanthrone

Datasheet MSDS
Catalog Number
SAUR11813
Product Name
Pyrazolanthrone
CAS Number
129-56-6
Synonyms
SP600125 , Nsc75890 , 1PMV , JNK Inhibitor II
Molecular Formula
C14H8N2O
Molecular Weight
220.23
Purity
99.58%
Solubility
DMSO: 22 mg/mL (100 mM) Ethanol: 1.1 mg/mL (5 mM)), with gentle warming ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
SP600125 is a JNK1/2/3 inhibitor (IC50: 40/40/90 nM) and 10-fold higher selectivity than MKK4, 25-fold higher selectivity than MKK3, MKK6, PKCα, and PKB.
Target
Aurora A, JNK1, JNK2, JNK3, TrkA
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