AG490

Datasheet MSDS
Catalog Number
SJAK10585
Product Name
AG490
CAS Number
133550-30-8
Synonyms
AG 490, AG-490, Tyrphostin AG 490, Zinc02557947, Tyrphostin B42
Molecular Formula
C17H14N2O3
Molecular Weight
294.3
Purity
99.70%
Solubility
Ethanol: 6 mg/mL (20.38 mM) DMSO: 59 mg/mL (200.47 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
AG-490 (Tyrphostin AG 490) is an inhibitor of EGFR (IC50: 0.1 μM). It is 135-fold more selective for EGFR than ErbB2, also inhibits JAK2 with no effect to Lyn, Lck, Syk, Btk, and Src.
Target
EGFR, HER2/ErbB2, JAK2
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