AG 494

Datasheet MSDS
Catalog Number
SEGF10194
Product Name
AG 494
CAS Number
133550-35-3
Synonyms
Tyrphostin AG-494, Tyrphostin B48, Tyrphostin B48, Tyrphostin AG-494
Molecular Formula
C16H12N2O3
Molecular Weight
280.28
Purity
99.50%
Solubility
Ethanol: 1.4 mg/mL (5 mM) DMSO: 14 mg/mL (50 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
AG-494 is an inhibitor of EGFR receptor autophosphorylation with an IC50 of 1.2 μM. It inhibits EGF-dependent cell growth with an IC50 of 6 μM.
Target
EGFR, EGFR kinase
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