Tyrphostin AG 528

Catalog Number
SEGF10190
Product Name
Tyrphostin AG 528
CAS Number
133550-49-9
Synonyms
AG 528, Tyrphostin B66, Tyrphostin B66, AG 528
Molecular Formula
C18H14N2O3
Molecular Weight
306.32
Purity
99.74%
Solubility
DMSO: 10 mM ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Tyrphostin AG-528 (Tyrphostin B66) is a potent inhibitor of epidermal growth factor receptors (EGFR) and ErbB2/HER2 with IC50 values of 4.9 μM and 2.1 μM, respectively. Tyrphostin AG-528 has anti-cancer activity.
Target
EGFR, ErbB2
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