Actinonin

Datasheet MSDS
Catalog Number
SAMI20521
Product Name
Actinonin
CAS Number
13434-13-4
Synonyms
(-)-Actinonin
Molecular Formula
C19H35N3O5
Molecular Weight
385.5
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces and a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM, it also is an apoptosis inducer. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase, it also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin has antiproliferative and antitumor activities[1][2][3][4][5].
Target
Peptide deformylase PDF
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