Catalog Number
A8223
Product Name
Avacopan
Structure
Avacopan
CAS Number
1346623-17-3
Synonyms
CCX168
Molecular Formula
C33H35F4N3O2
Molecular Weight
581.6
Purity
99.90%
Solubility
DMSO: 10.1 mg/mL (17.36 mM) DMSO: 10 mM ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Avacopan is an orally administered small-molecule C5aR ( IC50 : 0.1 nM.)antagonist that blocks the effects of C5a and prevents the development of GN induced by anti-myeloperoxidase antibodies in a murine model of AAV.
Target
complement 5a receptor C5aR
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