Catalog Number
SALK10019
Product Name
Vactosertib
CAS Number
1352608-82-2
Synonyms
TEW-7197, EW-7197, TEW-7197 EW-7197
Molecular Formula
C22H18FN7
Molecular Weight
399.42
Purity
99.81%
Solubility
DMSO: 73 mg/mL (182.8 mM) Ethanol: 40 mg/mL (100.1 mM) Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Ew-7197 is a highly effective, selective, oral bioeffective TGF-β receptor ALK4/ALK5 inhibitor with IC50 of 13 nM and 11 nM, respectively.
Target
ALK1, ALK2, ALK3, ALK4, ALK5
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