Vactosertib hydrochloride

Catalog Number
SALK10041
Product Name
Vactosertib hydrochloride
CAS Number
1352610-25-3
Synonyms
EW-7197 hydrochloride, TEW-7197 hydrochloride
Molecular Formula
C22H19ClFN7
Molecular Weight
435.88
Solubility
H2O: 50 mg/mL (114.71 mM), Need ultrasonic DMSO: 50 mg/mL (114.71 mM), Need ultrasonic ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Vactosertib Hydrochloride is an orally active and ATP-competitive ALK5 inhibitor (IC50: 12.9 nM). It has potently antimetastatic activity and anticancer effect. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50: 17.3 nM).
Target
ALK5
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