Catalog Number
SACE20469
Product Name
CMS-121
CAS Number
1353224-53-9
Synonyms
CMS121
Molecular Formula
C20H19NO3
Molecular Weight
321.37
Purity
99.48%
Solubility
DMSO: 50mg/mL (155.58mM), Need ultrasonic ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotective, antioxidative, anti-inflammatory, and renoprotective activities.
Target
Acetyl-CoA carboxylase 1 (ACC1)
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