Crizotinib hydrochloride

Catalog Number
SALK10049
Product Name
Crizotinib hydrochloride
CAS Number
1415560-69-8
Synonyms
PF-02341066 hydrochloride
Molecular Formula
C21H23Cl3FN5O
Molecular Weight
486.8
Purity
99.67%
Solubility
DMSO: 4.9 mg/mL (10.07 mM) H2O: 50 mg/mL (102.71 mM), Need ultrasonic ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Crizotinib hydrochloride is a potent inhibitor of c-Met and ALK with IC50s of 11 nM and 24 nM in cell-based assays, respectively.
Target
anaplastic lymphoma kinase, c-Met
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