PR-924

Datasheet MSDS
Catalog Number
SPRO27956
Product Name
PR-924
CAS Number
1416709-79-9
Molecular Formula
C37H38N4O5
Molecular Weight
618.72
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM). PR-924 inhibits growth and triggers apoptosis in multiple myeloma (MM) cells. PR-924 has antitumor activities. PR-924 covalently modifies proteasomal N-terminal threonine active sites.
Target
LMP7, LMP2
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