GZD824 Dimesylate

Catalog Number
SBCR10080
Product Name
GZD824 Dimesylate
CAS Number
1421783-64-3
Synonyms
HQP1351
Molecular Formula
C29H27F3N6O·2CH4O3S
Molecular Weight
724.77
Purity
100.00%
Solubility
DMSO: 93 mg/mL (128.3 mM) Water: 92 mg/mL (126.9 mM) Ethanol: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
GZD824 Dimesylate is a novel orally potent Bcr-Abl inhibitor acting on Bcr-Abl (WT) and Bcr-Abl (T315I) with IC50 of 0.34 nM and 0.68 nM, respectively.
Target
Abl, Abl (E255K), Abl (H396P), Abl (M351T), Abl (Q252H)
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