AKI603

Datasheet MSDS
Catalog Number
SAUR11841
Product Name
AKI603
CAS Number
1432515-73-5
Synonyms
AKI 603 , AKI-603
Molecular Formula
C19H23N9O2
Molecular Weight
409.45
Purity
99.81%
Solubility
DMSO: 120 mg/mL (293.07 mM), Need ultrasonic ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in leukemic cells[1][2].
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