Catalog Number
SALK10013
Product Name
Lorlatinib
CAS Number
1454846-35-5
Synonyms
PF-06463922, PF-6463922, Loratinib
Molecular Formula
C21H19FN6O2
Molecular Weight
406.41
Purity
100.00%
Solubility
DMSO: 40.6 mg/mL (100 mM) Ethanol: 40.6 mg/mL (100 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
RDEA119 is a potent, non-ATP-competitive, highly selective MEK1 and MEK2 inhibitor with IC50 of 19 nM and 47 nM, respectively.
Target
ALK, ALK (L1196M), LTK (TYK1), ROS1
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