G749

Datasheet MSDS
Catalog Number
SFLT10462
Product Name
G749
CAS Number
1457983-28-6
Synonyms
G 749, G-749
Molecular Formula
C25H25BrN6O2
Molecular Weight
521.41
Purity
100.00%
Solubility
DMSO: 23 mg/mL (44.1 mM) Ethanol: <1 mg/mL Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
G-749 is a novel potent FLT3 inhibitor with 0.4 nM, 0.6 nM and 1 nM for FLT3 (WT), FLT3 (D835Y), and Mer IC50, respectively, which have low effects on other tyrosine kinases
Target
Aurora B, FLT3, FLT3 (D835Y), Mer, RET
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