Pralatrexate

Datasheet MSDS
Catalog Number
SDHF12143
Product Name
Pralatrexate
CAS Number
146464-95-1
Synonyms
Folotyn , 10-Propargyl-10-deazaaminopterin
Molecular Formula
C23H23N7O5
Molecular Weight
477.47
Purity
98.12%
Solubility
DMSO: 27 mg/mL (56.5 mM) Ethanol: <1 mg/mL Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Pralatrexate is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities.
Target
DHFR, Axl(KPL-4 cells ), Axl(SUM149 cells)
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