Docetaxel trihydrate

Datasheet MSDS
Catalog Number
SBCL10874
Product Name
Docetaxel trihydrate
CAS Number
148408-66-6
Synonyms
RP-56976 (Trihydrate) , RP56976 (NSC 628503) Trihydrate
Molecular Formula
C43H59NO17
Molecular Weight
861.95
Purity
100.00%
Solubility
Ethanol: 100 mg/mL (116.01 mM) DMSO: 100 mg/mL (116.01 mM) Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Docetaxel is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis and that currently plays a central role in the therapy of many solid tumor including breast and lung cancer. Therapy with docetaxel has been associated with a low rate of serum enzyme elevations and rarely to instances of acute hepatic necrosis generally due to severe hypersensitivity reactions or sepsis.
Target
Bcl-2, Tubulin β-1 chain
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