Pemetrexed disodium

Catalog Number
SDHF12144
Product Name
Pemetrexed disodium
CAS Number
150399-23-8
Synonyms
LY231514 disodium , Pemetrexed , LY-231514
Molecular Formula
C20H19N5Na2O6
Molecular Weight
471.37
Purity
99.92%
Solubility
DMSO: 10mM ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Pemetrexed is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed therapy has been associated with moderate rates of serum enzyme elevations during therapy, but has not been convincingly linked to instances of acute, clinically apparent liver injury.
Target
DHFR, GARFT, Thymidylate synthase
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