Catalog Number
SBCR10060
Product Name
Imatinib
CAS Number
152459-95-5
Synonyms
STI571, CGP057148B, ST-1571, STI571, ST-1571, CGP057148B
Molecular Formula
C29H31N7O
Molecular Weight
493.6
Purity
99.94%
Solubility
DMSO: 66.9 mM ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Imatinib (STI571, CGP057148B, ST-1571) is a multi-target tyrosine kinase inhibitor with IC50 inhibiting v-Abl, c-Kit, and PDGFR at 0.6, 0.1, and 0.1 μM, respectively. Imatinib (STI571) induces autophagy.
Target
c-Kit, PDGFR, v-Abl
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