Catalog Number
SDUB29517
Product Name
ML323
CAS Number
1572414-83-5
Molecular Formula
C23H24N6
Molecular Weight
384.48
Purity
99.96%
Solubility
DMSO: 38.5 mg/mL (100 mM) Ethanol: 38.5 mg/mL (100 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
ML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay (IC50: 76 nM) and in orthogonal gel-based assays using K63-linked diubiquitin (di-Ub) (IC50: 174 nM 820 nM)and monoubiquitinated PCNA (Ub-PCNA) (IC50: 820 nM) as substrates, respectively.
Target
USP1-UAF1
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