ATR inhibitor 2

Catalog Number
SATM14132
Product Name
ATR inhibitor 2
CAS Number
1613191-99-3
Molecular Formula
C25H29F2N9O3
Molecular Weight
541.55
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
ATR inhibitor 2 is an orally active, ATP-competitive, and selective ATR inhibitor (Ki <150 pM) with antitumor activity. ATR inhibitor 2 potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (Chk1) phosphorylation (IC50: 8 nM).
Target
ATR
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