AZD3759 hydrochloride

Datasheet MSDS
Catalog Number
SEGF10193
Product Name
AZD3759 hydrochloride
CAS Number
1626387-81-2
Molecular Formula
C22H24Cl2FN5O3
Molecular Weight
496.36
Purity
99.41%
Solubility
DMSO: 10 mM ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrant EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.2/0.3/0.2 nM for EGFR (L858R)/EGFR (wt)/EGFR (exon 19Del).
Target
EGFR (exon 19De), EGFR (L858R), EGFR (wt), EGFR
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