Catalog Number
SBMI11865
Product Name
PTC-028
CAS Number
1782970-28-8
Molecular Formula
C19H12F5N5
Molecular Weight
405.32
Purity
98.25%
Solubility
DMSO: 125 mg/mL (308.40 mM), Need ultrasonic ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspase-mediated apoptosis.
Target
BMI-1
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