Erlotinib

Datasheet MSDS
Catalog Number
SEGF10169
Product Name
Erlotinib
CAS Number
183321-74-6
Synonyms
OSI-744, R1415, NSC 718781, CP358774
Molecular Formula
C22H23N3O4
Molecular Weight
393.44
Purity
99.98%
Solubility
DMSO: 72 mg/mL (183 mM) Ethanol: 12 mg/mL (30.5 mM) Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Erlotinib (OSI-774, CP358774, NSC 718781, Tarceva) is an EGFR inhibitor with an IC50 of 2 nM and is more than 1000 times more sensitive to EGFR than to human c-Src or v-Ab. Erlotinib induces autophagy.
Target
EGFR
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