Gefitinib

Datasheet MSDS
Catalog Number
SEGF10167
Product Name
Gefitinib
CAS Number
184475-35-2
Synonyms
ZD1839
Molecular Formula
C22H24ClFN4O3
Molecular Weight
446.91
Purity
100.00%
Solubility
DMSO: 44.7 mg/mL (100 mM) Ethanol: 4.5 mg/mL (10 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Gefitinib is an EGFR tyrosine kinase inhibitor and can inhibit Tyr1173, Tyr992, Tyr1173 and Tyr992 (IC50s: 37/37/26/57 nM).
Target
Tyr1173 (NR6W cells), Tyr1173 (NR6wtEGFR cells), Tyr992 (NR6W cells), Tyr992 (NR6wtEGFR cells), Tyr1173, Tyr992
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