Catalog Number
SDUB29521
Product Name
GNE6640
CAS Number
2009273-67-8
Synonyms
GNE-6640 , GNE 6640 , GNE-6640 GNE 6640
Molecular Formula
C20H18N4O
Molecular Weight
330.39
Purity
99.59%
Solubility
DMSO: 5 mg/mL (15.13 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
GNE-6640 is a non-covalent inhibitor of ubiquitin epecific peptidase 7 (USP7), with IC50 values of 0.75 μM, 0.43 μM, 20.3 μM and 0.23 μM for full length USP7, USP7 catalytic domain, full length USP43 and Ub-MDM2, respectively.
Target
full length USP7, USP7 catalytic domain, full length USP43, Ub-MDM2
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