DAPT

Datasheet MSDS
Catalog Number
SBET24966
Product Name
DAPT
CAS Number
208255-80-5
Synonyms
GSI-IX , LY-374973 , LY-374973 , GSI-IX
Molecular Formula
C23H26F2N2O4
Molecular Weight
432.46
Purity
99.79%
Solubility
DMSO: 43.2 mg/mL (100 mM), 100 mM Water: Insoluble ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
DAPT is a novel γ-secretase inhibitor which reduces the Aβ production (IC50: 20 nM in HEK 293 cells) and Aβ42 levels (IC50: 200 nM).
Target
γ secretase(Aβ), Aβ, Aβ42
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