JNJ-63576253

Catalog Number
SAND14960
Product Name
JNJ-63576253
CAS Number
2110426-27-0
Synonyms
TRC253
Molecular Formula
C23H21F3N6O2S
Molecular Weight
502.51
Purity
98.32%
Solubility
DMSO: 10 mM ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
JNJ-63576253 is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells. JNJ-63576253 can be used for the research of castration-resistant prostate cancer (CRPC).
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