ATM inhibitor-1

Datasheet MSDS
Catalog Number
SATM14131
Product Name
ATM inhibitor-1
CAS Number
2135639-94-8
Molecular Formula
C27H36N6O3
Molecular Weight
492.61
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
ATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibito (IC50: 0.7 nM) anti-tumor activity. It shows weak activity against mTOR (IC50, 21 μM), DNAPK (IC50, 2.8 μM), PI3Kα (IC50, 3.8 μM), PI3Kβ (IC50, 10.3 μM), PI3Kγ (IC50, 3 μM) and PI3Kδ (IC50, 0.73 μM).
Target
ATM, PI3Kδ, PI3Kγ, PI3Kα, PI3Kβ, DNAPK, mTOR
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