Catalog Number
SAND14972
Product Name
UT-34
CAS Number
2168525-92-4
Molecular Formula
C15H12F4N4O2
Molecular Weight
356.27
Purity
98.10%
Solubility
DMSO: 71 mg/mL (199.29 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader(IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-type, F876L and W741L AR, respectively), and has anti-prostate cancer efficacy.
Target
Wild-type AR, F876L AR, W741L AR, androgen receptor
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