Jagged-1 (188-204)

Catalog Number
SGAM25631
Product Name
Jagged-1 (188-204)
CAS Number
219127-21-6
Synonyms
Jagged-1 188-204
Molecular Formula
C93H127N25O26S3
Molecular Weight
2107.4
Purity
99.48%
Solubility
DMSO: 10 mM ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
This peptide is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-αB activation.
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