Tretazicar

Datasheet MSDS
Catalog Number
SDNA14173
Product Name
Tretazicar
CAS Number
21919-05-1
Synonyms
CB1954 , 5-Aziridino-2,4-dinitrobenzamide , NSC 115829 , NSC 115829 , 5-Aziridino-2,4-dinitrobenzamide , CB1954
Molecular Formula
C9H8N4O5
Molecular Weight
252.18
Purity
99.70%
Solubility
DMSO: 47 mg/mL (186.4 mM) Ethanol: <1 mg/mL Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
CB1954(Tretazicar), an anticancer prodrug, is activated by NAD(P)H quinone oxidoreductase 2. It is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent.
Target
Others
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