PD173074

Datasheet MSDS
Catalog Number
SEGF10187
Product Name
PD173074
CAS Number
219580-11-7
Molecular Formula
C28H41N7O3
Molecular Weight
523.67
Purity
99.33%
Solubility
DMSO: 52.4 mg/mL (100 mM) Ethanol: 52.4 mg/mL (100 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
PD173074 is a potent FGFR1 inhibitor, IC50 is about 25nM in cell-free tests, can also inhibit VEGFR2, IC50 is 100-20Chemicalbook0nM, acting on FGFR1 is about 1000 times more selective than acting on PDGFR and c-Src. PD173074 inhibits proliferation and promotes apoptosis in gastric cancer cells.
Target
c-Src, EGFR, FGFR1, Insulin Receptor, VEGFR2
Inquiry

new products