Catalog Number
SCDK11974
Product Name
NU6027
CAS Number
220036-08-8
Molecular Formula
C11H17N5O2
Molecular Weight
251.28
Purity
99.85%
Solubility
DMSO: 47 mg/mL (187 mM) Ethanol: 3 mg/mL (11.93 mM) Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-aminopurine-based inhibitors.
Target
ATR, CDK1, CDK2, DNA-PK
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