Imatinib mesylate

Catalog Number
SBCR10061
Product Name
Imatinib mesylate
CAS Number
220127-57-1
Synonyms
STI-571, CGP-57148B, ST-1571 Mesylate
Molecular Formula
C29H31N7O·CH4SO3
Molecular Weight
589.71
Purity
100.00%
Solubility
DMSO: 59 mg/mL (100 mM) water: 59 mg/mL (100 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Imatinib Mesylate (STI571, CGP-57148B) is an orally bioavailable Imatinib mesylate, a multi-target inhibitor that acts on v-Abl, c-Kit, and PDGFR, with IC50s of 0.6 μM, 0.1 μM, and 0.1 μM, respectively, in cell-free and cell-free and cell-free trials. Imatinib Mesylate (STI571) induces autophagy.
Target
c-Kit, PDGFR, v-Abl
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