F-1

Datasheet MSDS
Catalog Number
SALK10039
Product Name
F-1
CAS Number
2244775-31-1
Molecular Formula
C22H27ClN8O3S
Molecular Weight
519.02
Solubility
DMSO: 100 mg/mL (192.67 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
F-1 is an effective dual inhibitor of ALK and ROS1, inhibiting ALK phosphorylation and downstream pathways, with IC50 values of 2.1nM, 2.3nM, 1.3nM and 3.9nM for ALKWT, ROS1WTChemicalbook, ALKL1196M and ALKG1202R, respectively.
Target
Others
Inquiry

new products