KI8751

Datasheet MSDS
Catalog Number
SEGF10210
Product Name
KI8751
CAS Number
228559-41-9
Molecular Formula
C24H18F3N3O4
Molecular Weight
469.41
Purity
99.90%
Solubility
DMSO: 46.9 mg/mL (100 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Ki8751 is a potent, selective VEGFR2 inhibitor with an IC50 of 0.9 nM, acting on VEGFR2 more than 40 times more selective than acting on Chemicalbookc-Kit, PDGFRα and FGFR-2, with no inhibitory activity against EGFR, HGFR and InsR.
Target
c-Kit, EGFR, FGFR2, PDGFRα, VEGFR2
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