Physalin A

Datasheet MSDS
Catalog Number
SJAK10610
Product Name
Physalin A
CAS Number
23027-91-0
Molecular Formula
C28H30O10
Molecular Weight
526.5
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate cancer cell growth through activation of cell apoptosis and downregulation of androgen receptor expression. Physalin A induces apoptosis via p53-Noxa-mediated ROS generation, and autophagy plays a protective role against apoptosis through p38-NF-κB survival pathway in A375-S2 cells.
Target
Androgen Receptor, Autophagy, Bcl-2, ERK, JAK, JNK, NF-κB, p38 MAPK, p53, ROS, STAT
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